Next-generation sequencing applications, such as ChIP-Seq, RNA-Seq, RIP-Seq, exome sequencing, and whole genome sequencing require precise sample fragmentation (200-600 bp) for compatibility with short read sequencing platforms. Shearing by physical sonication, as opposed to enzymatic methods, is preferred for its unbiased nature and ability to produce a relatively narrow fragmentation profile.

However, most currently available sonication systems are incompatible with high-throughput sample processing or require expensive proprietary plates or tubes. PIXUL is the first and only multi-sample sonicator that delivers extremely consistent shearing of up to 96 samples processed in parallel and is fast, simple, and inexpensive to operate.

PIXUL Multi-Sample Sonicator Highlights:

Consistent: Process 1-96 samples simultaneously with extremely high reproducibility.

Simple: Fast setup, short learning curve, and easy operation with intuitive touchscreen.

Fast: Arrayed transducers and no degassing required saves time.

Flexible: Use up to 12 different sonication conditions per run in 96-well plates for simultaneous processing of DNA, RNA, and protein sample types.

Affordable: No requirement for buying accessories or expensive proprietary plates or tubes.

Unsurpassed Sonication Consistency at an Affordable Operating Cost

High-throughput sonication on other platforms is currently limited by the cost of consumables (expensive proprietary tubes, plates, and reagents). However, the low cost, round-bottom plates used with the PIXUL Multi-Sample Sonicator are directly compatible with cell culture and shearing, eliminating sample transfer steps that are inconvenient and can lead to sample loss. Furthermore, the Coupling Fluid used in the PIXUL instrument does not require lengthy degassing and can be adequately circulated and ready for sonication in approximately 15 minutes. The sonication run itself for up to 96 samples takes just 10-30 minutes, depending on the sample type and application.

Specifications:

Dimensions (h, d, w): 45 cm x 59 cm x 34 cm (17.7 in x 23 in x 13 in)
Weight: 23 kg (50.7 lbs)
Power Requirements: 100-240 VAC, 50-60Hz, 6 A max. at 115 VAC, 700 W
Operating Environment: 15°C to 25°C (59°F to 77°F), max. 85% relative humidity
Storage Temperature: 5°C to 25°C (41°F to 77°F)
EMC: Complies with EN IEC 61326-1, “Electrical equipment for measurement, control and laboratory use – EMC requirements – Part 1: General requirements”, Class A. Complies with FCC Part 15 Class A and FCC part 18 radio emissions requirements for the USA and ICES-001 and ICES-003 for Industry Canada. Complies with EU EMC Directive 2014/30/EU.
Safety Certification:

- - UL Listing – certified to comply with UL #61010-1, 3rd Edition cUL
  - Listing – certified to comply with CAN/CSA C222.2 No.
  - 61010-1-12, 3rd edition.
  - IEC 61010-2-081 . Particular requirements for automatic and semi-automatic
  - laboratory equipment for analysis and other purposes
  - CE Mark – complies with EN/IEC 61010-1 3rd edition.
  - Under Ul file # E513812-D1000

Operating System: User interface, software and processors are fully integrated into the instrument.
Chiller: Chiller is fully integrated into the instrument.
Sample Processing Capacity: Sample processing uses round bottom 96-well microplates (Corning Cat. No. 3799), 200 µL per well
Recommended Batch Size: 1 to 96
Applications: DNA Shearing, RNA Shearing, Chromatin Shearing, Protein Extraction

Weight	26 lbs
Dimensions	22 × 18 × 14 in
Brand	Active Motif
Condition	Used
MPN	53130
Product Type	4335 – Business & Industrial > Science & Laboratory > Laboratory Equipment